Preheat Oven: Start by preheating your oven to 400°F (200°C).
Cook the Beef: In a large skillet over medium heat, add the ground beef and diced onions. Cook until the beef is browned and the onions are softened. Drain excess fat.
Season the Mixture: Add ketchup, mustard, Worcestershire sauce, salt, and pepper to the skillet. Stir to combine, letting it cook for an additional 2-3 minutes to let the flavors meld together.
Add Cheese: Remove from heat and allow the beef mixture to cool slightly, then stir in the shredded cheese and optional diced pickles. Set aside.
2. Make the Bisquick Crust
Mix Ingredients: In a mixing bowl, whisk together Bisquick, milk, and eggs until smooth. This mixture will form both the base and top layers of the pie.
Pour Half the Batter: Lightly grease a 9-inch pie dish, and pour half of the Bisquick mixture into the bottom, spreading it to cover the base.